Rimonabant service01@chembj.com
Ad number 2227461, visitors 1310
Placed: 28/03/16
Region: Aberdeen
Location: China
Category: Health and Beauty
Content of the advertisement:
Rimonabant
Synonyms: ACOMPLIA;RIMONABANT;RIMONABANT(ACOMPLIA,SR141716);5-(4-
Chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-piperidinopyrazole-3-
carboxamide;1H-Pyrazole-3-carboxamide, 5-(4-chlorophenyl)-1-(2,4-
dichlorophenyl)-4-methyl-N-1-piperidinyl-;5-(4-Chlorophenyl)-1-(2,4-
dichlorophenyl)-4-methyl-N-1-piperidinyl-1H-pyrazole-3-carboxamide;A
281;Sr 141716
CAS: 168273-06-1
MF: C22H21Cl3N4O
MW: 463.79
Product Categories: Weight Loss;SR141716
Mol File: 168273-06-1.mol
Usage: Rimonabant is a selective antagonist of CB1 with IC50 of 13.6 nM
and EC50 of 17.3 nM in hCB1 transfected HEK 293 membrane
Rimonabant Brief introduction:
Rimonabant has also been shown to be a μ-opioid receptor antagonist
(possibly the contributing factor in its reported dysphoric
qualities).Its main effect is reduction in appetite.
Rimonabant Application:
Obesity
In a 2006 (2 year) study reported in JAMA, "Compared with the placebo
group, the 20 mg of rimonabant group produced greater mean (SEM)
reductions in weight (-6.3 [0.2] kg vs -1.6 [0.2] kg; P
Price / Salary: £1.00