Scientist - 12 Month Fixed Term

Placed: 08/12/17
Region: Oxfordshire
Location: Oxford
Category: Jobs


Content of the advertisement:

**Job purpose** :

To plan and carry out experimental work towards the discovery, development and improvement of gene therapies currently under development within the group.

**Key responsibilities and accountabilities:**

* Development and improvement in gene therapies utilising the OXB lentiviral vector platform

* Agree objectives with the line manager in-line with company and research group objectives, and be responsible for achieving them in the agreed time frame where possible.
* With the line manager, ensure that they have received the appropriate level of training for safe, effective and GxP-compliant aspects of their work, and personally ensure that this is captured in their training record.
* Independently plan, manage and execute experimental work in line with the research objectives as directed and agreed with their line manager.

* Have excellent knowledge of project area literature and ensure the group is up to date with current thinking and literature.
* Maintain a high ethical standard and a commitment to producing high quality work.
* Report results to the group and head of department either as written reports or at internal meetings
* Responsible for ensuring all scientific data is submitted to PatentSafe or recorded in appropriate official documentation.
* If relevant, supervise junior members of the team at day-to-day technical level and/or by directing their research projects in collaboration with the line manager.
* Support other members of the team and wider the Research Group as required

**** **Key skills and requirements:**

* PhD or equivalent in relevant Bioscience (e.g. virology, molecular and/or cellular biology) and have several years post-doctoral experience in academia or industry
* Excellent lab-based skills with particular emphasis on molecular biology that include but not limited to: DNA/microbial cloning RT-/PCR, qPCR, immunoblotting and cell biology techniques that include but not limited to: cell culture (adherent/suspension), cell transfection, viral vector production/purification, immunofluorescence and flow cytometry
* Excellent written and verbal communication skills
* Excellent organisational and time management skills
* Good attention to detail
* Highly motivated
* Ability to execute projects to aggressive timelines with the ability to adapt to rapid changes in project priorities.
* Expertise in lentiviral vector gene therapies a distinct advantage.

**Person Specification:**

* Industry experience in gene or cell therapies for disease with ocular or neurological disease experience preferable
* Knowledge and experience of developing viral vector based therapies
* A highly motivated, enthusiastic, positive attitude
* Ability to demonstrate (by peer-reviewed publications) the ability to work independently, and with a good understanding of the field they are working within
* Ability to work well in a team setting, and when appropriate ensure others are able to perform the tasks to the benefit of the team objective.

**** **About Early Development/Discovery and Design Group**

The Discovery and Design group is part of the broader Early development group which has a core function in the Research department to discover and develop new gene and cell therapies to treat disease.

**Closing Date: 12th January 2018**

**How to Apply**

Please use the questionnaire to highlight how you meet the competencies for the role and to state your salary requirements and current salary. Your questionnaire responses will be used along with your CV to assess your application.

Please note that speculative CVs will not be considered.

**Please note that we may when necessary be required to close a job prior to the closing date, due to a large number of applications or change in circumstance.

* The post will close on the closing date stated at midnight *

It is company policy that travel expenses will not be reimbursed. **

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Price / Salary: Competitive